1) Collagenosis, connective tissue disease: - Progressive outbreaks of systemic diseases, in particular: systemic lupus erythematosus, vasculitis, polymyositis, visceral sarcoidosis. 2) Dermatological: - Severe autoimmune bullous dermatoses, in particular pemphigus and bullous pemphigoid. - Serious forms of angiomas in infants. - Certain forms of lichen planus. - Certain acute urticaria. - Serious forms of neutrophilic dermatoses. 3) Digestive: - Progressive outbreaks of ulcerative colitis and Crohn's disease. - Chronic active autoimmune hepatitis (with or without cirrhosis). - Severe acute alcoholic hepatitis, histologically proven. 4) Endocrine: - Severe subacute de Quervain thyroiditis. - Certain hypercalcemia. 5) Hematological: - Severe immunological thrombocytopenic purpuras. - Autoimmune hemolytic anemia. - In combination with various chemotherapies in the treatment of lymphoid malignancies. - Chronic, acquired or congenital erythroblastopenia. 6) Infectious: - Tuberculous pericarditis and serious forms of life-threatening tuberculosis. - Pneumocystis carinii pneumonia with severe hypoxia. 7) Neoplastics: - Antiemetic treatment during antineoplastic chemotherapy. - Edematous and inflammatory flare-up associated with antineoplastic treatments (radio and chemotherapy). 8) Nephrological: - Nephrotic syndrome with minimal glomerular lesions. - Nephrotic syndrome of primary segmental and focal hyalinoses. - Stages III and IV of lupus nephropathy. - Intrarenal granulomatous sarcoidosis. - Vasculitis with renal damage. - Primary extracapillary glomerulonephritis. 9) Neurological: - Myasthenia. - Cerebral edema of tumor cause. - Chronic, idiopathic, inflammatory polyradiculoneuropathy. - Infantile spasm (West syndrome), Lennox-Gastaut syndrome. - Multiple sclerosis in flare-up, following intravenous corticosteroid therapy. 10) Ophthalmological: - Severe anterior and posterior uveitis. - Edematous exophthalmos. - Certain optic neuropathies, following intravenous corticosteroid therapy (in this indication, the oral route as first intention is not recommended). 11)ENT: - Certain serous otitis. - Nasosinusal polyposis. - Certain acute or chronic sinusitis. - Seasonal allergic rhinitis in short course. - Acute stridular laryngitis (subglottic laryngitis) in children. 12) Respiratory: - Persistent asthma preferably in a short course in the event of failure of high-dose inhalation treatment. - Exacerbations of asthma, particularly severe acute asthma. - Chronic obstructive pulmonary disease in evaluation of the reversibility of the obstructive syndrome. - Progressive sarcoidosis. - Diffuse interstitial pulmonary fibrosis. 13) Rheumatological: - Rheumatoid arthritis and certain polyarthritis. - Rhizomelic pseudopolyarthritis and Horton's disease. - Acute articular rhumatism. - Severe and intractable cervicobrachial neuralgia. 14) Allogeneic organ and hematopoietic stem cell transplantation: - Prophylaxis or treatment of graft rejection. - Prophylaxis or treatment of graft-versus-host disease.