Conditions or diseases: - Collagenosis, connective tissue disease: Progressive outbreaks of systemic diseases, in particular: systemic lupus erythematosus, vasculitis, polymyositis, visceral sarcoidosis. - Dermatological: Severe autoimmune bullous dermatoses, in particular pemphigus and bullous pemphigoid. Severe forms of angiomas in infants. Certain forms of lichen planus. Some acute urticaria. Severe forms of neutrophilic dermatoses. - Digestive: Progressive outbreaks of ulcerative colitis and Crohn's disease. Chronic active autoimmune hepatitis (with or without cirrhosis). Severe acute alcoholic hepatitis, histologically proven. - Endocrine: Severe subacute de Quervain thyroiditis. Certain hypercalcemias. - Hematological: Severe immunological thrombocytopenic purpuras. Autoimmune hemolytic anemias. In combination with various chemotherapies in the treatment of lymphoid malignancies. Chronic, acquired or congenital red cell aplasia. - Infectious: Tuberculous pericarditis and serious forms of life-threatening tuberculosis. Pneumocystis carinii pneumonia with severe hypoxia. - Neoplastics: Antiemetic treatment during antineoplastic chemotherapy. Edematous and inflammatory flare-up associated with antineoplastic treatments (radio and chemotherapy). - Nephrological: Nephrotic syndrome with minimal glomerular lesions. Nephrotic syndrome of primary segmental and focal hyalinoses. Stages III and IV of lupus nephropathy. Intrarenal granulomatous sarcoidosis. Vasculitis with renal damage. Primary extracapillary glomerulonephritis. - Neurological: Myasthenia. Cerebral edema caused by tumor. Chronic, idiopathic, inflammatory polyradiculoneuritis. Infantile spasm (West syndrome), Lennox-Gastaut syndrome. Multiple sclerosis in flare-up, following intravenous corticosteroid therapy. - Ophthalmological: Severe anterior and posterior uveitis. Edematous exophthalmos.Certain optic neuropathies, following intravenous corticosteroid therapy (in this indication, the oral route as first intention is not recommended). - ENT: Certain serous ear infections. Nasosinusal polyposis. Certain acute or chronic sinusitis. Seasonal allergic rhinitis in short course. Acute stridular laryngitis (subglottic laryngitis) in children. Respiratory: Persistent asthma preferably in a short course in the event of failure of high-dose inhalation treatment. Exacerbations of asthma, especially severe acute asthma. Chronic obstructive pulmonary disease in evaluation of the reversibility of the obstructive syndrome. Progressive sarcoidosis. Diffuse interstitial pulmonary fibrosis. - Rheumatological: Rheumatoid arthritis and certain polyarthritis. Rhizomelic pseudopolyarthritis and Horton's disease. Acute articular rhumatism. Severe and intractable cervicobrachial neuralgia. - Organ and allogeneic hematopoietic stem cell transplantation: Prophylaxis or treatment of graft rejection. Prophylaxis or treatment of graft-versus-host disease.